DNA Vaccine Administration Through Transdermal Delivery Systems

Infectious disease is a global problem and it effects almost all sections of peoples. A number of microorganisms are available to cause a variety of diseases. The infectious disease has tremendous impact on human health which has made the life miserable. The basic treatment for the infectious disese is the use of antimicrobials and the use of vaccination. Both of the above methods have the sideffects. This has lead to the innovation of DNA vaccine which is comparatively more effective and valuable. DNA vaccination is a technology which utilizes genetically engineered DNA to produce an immunologic response which provides immunity. This article is totally based on literature survey. This review will put major emphasis on the on the administration of DNA vaccine through transdermal delivery system. The authors explored the types of transdermal delivery systems like Iontophoresis, Devices based on velocity, Microneedles, Radiofrequencyinduced microporation, Laser microporation and Sonophoresis. Much focused were made on merits and demerits the transdelivery systems. The future prospects of this delivery systems were also highlighted. The aim of compiling this article is to help those researchers who are doing research with DNA vaccine. They will come to know about the delivery of DNA vaccine through transdermal delivery systems. This will help them to reach to their target in concerned with this Vaccine.